\u9577\u4e45\u4ee5\u4f86\u79d1\u5b78\u5bb6\u90fd\u61f7\u7591\uff0c1907\u5e74\u7531\u963f\u8332\u6d77\u9ed8\u91ab\u751f\u767c\u73fe\u7684\u86cb\u767d\u8cea\u5718\u584a\u53ca\u7cfe\u7d50\uff0c\u53ef\u80fd\u9020\u6210\u795e\u7d93\u5143\u6b7b\u4ea1\uff0c\u4e26\u9032\u800c\u5f15\u767c\u963f\u8332\u6d77\u9ed8\u75c7\u3002\u5982\u4eca\uff0c\u6709\u4e9b\u7814\u7a76\u4eba\u54e1\u5c07\u8a72\u75c5\u6b78\u7f6a\u65bc\u4e00\u7a2e\u5f62\u72c0\u5c0f\u5f97\u591a\u7684\u86cb\u767d\uff1b\u9019\u7a2e\u86cb\u767d\u53ea\u8981\u8207\u795e\u7d93\u5143\u76f8\u63a5\uff0c\u5c31\u53ef\u5e72\u64fe\u795e\u7d93\u5143\u50b3\u905e\u8a0a\u606f\u7684\u80fd\u529b\uff0c\u800c\u9020\u6210\u8a18\u61b6\u7684\u7f3a\u5931\u3002<\/p>\n
\u76ee\u524d\uff0c\u5df2\u6709\u4eba\u8457\u624b\u5c0b\u6c42\u53ef\u6467\u6bc0\u9019\u7a2e\u7a31\u70baADDL\u5c0f\u578b\u86cb\u767d\u7684\u6297\u9ad4\uff0c\u5e0c\u671b\u80fd\u9810\u9632\u9019\u7a2e\u75be\u75c5\u7684\u767c\u4f5c\uff0c\u751a\u81f3\u53ef\u80fd\u626d\u8f49\u521d\u671f\u7684\u75c7\u72c0\u3002<\/p>\n
<\/p>\n
ADDL\u7684\u767c\u73fe\uff0c\u6216\u53ef\u89e3\u91cb\u9019\u7a2e\u75be\u75c5\u7684\u50b3\u7d71\u770b\u6cd5\uff0c\u70ba\u4f55\u5145\u6eff\u4f8b\u5916\u3002\u50b3\u7d71\u5c0d\u963f\u8332\u6d77\u9ed8\u75c7\u7684\u770b\u6cd5\u662f\uff1a\u7531\u6b63\u5e38\u795e\u7d93\u5143\u6240\u88fd\u9020\u7684\u985e\u6fb1\u7c89\u524d\u9a45\u86cb\u767d\u7247\u6bb5\uff0c\u805a\u96c6\u6210\u5177\u9ecf\u6027\u4e14\u7121\u6cd5\u6eb6\u89e3\u7684\u6591\u584a\uff0c\u4ee5\u81f4\u50b7\u5bb3\u4e86\u795e\u7d93\u5143\u3002\u9019\u5957\u7406\u8ad6\u7684\u554f\u984c\u662f\uff0c\u5e7e\u4e4e\u6bcf\u4f4d\u8001\u5e74\u4eba\u90fd\u5e36\u6709\u4e00\u4e9b\u985e\u6fb1\u7c89\u86cb\u767d\u6591\uff0c\u4f46\u53ea\u6709\u5c11\u6578\u4eba\u624d\u51fa\u73fe\u963f\u8332\u6d77\u9ed8\u75c7\uff1b\u800c\u4e14\uff0c\u963f\u8332\u6d77\u9ed8\u75c7\u60a3\u8005\u6240\u5e36\u6709\u7684\u6591\u584a\uff0c\u901a\u5e38\u6578\u76ee\u9084\u66f4\u5c11\u3002\u53e6\u4e00\u500b\u906d\u5230\u9ede\u540d\u7684\u7f6a\u9b41\u798d\u9996\uff0c\u662f\u51fa\u73fe\u5728\u795e\u7d93\u5143\u5167\u90e8\u7684tau\u86cb\u767d\u7cfe\u7d50\uff0c\u4f34\u96a8\u8457\u652f\u6301\u7d30\u80de\u672c\u9ad4\u53ca\u8ca0\u8cac\u8f38\u9001\u990a\u4efd\u7684\u5fae\u5c0f\u7ba1\u74e6\u89e3\u3002tau\u86cb\u767d\u7cfe\u7d50\u8207\u963f\u8332\u6d77\u9ed8\u75c7\u7684\u95dc\u806f\u8f03\u4f73\uff0c\u4f46\u51fa\u73fe\u7684\u6642\u9593\u901a\u5e38\u8f03\u665a\uff0c\u986f\u793a\u90a3\u662f\u8a72\u75c5\u9020\u6210\u7684\u7d50\u679c\uff0c\u800c\u975e\u7522\u751f\u75be\u75c5\u7684\u539f\u56e0\u3002 1994\u5e74\uff0c\u7f8e\u570b\u5357\u52a0\u5927\u7684\u795e\u7d93\u8001\u4eba\u5b78\u5bb6\u82ac\u5947\u5c07\u985e\u6fb1\u7c89\u524d\u9a45\u86cb\u767d\u7247\u6bb5\u4ee5\u53ca\u7fa4\u96c6\u7d20\uff08clusterin\uff09\u5728\u6eb6\u6db2\u4e2d\u6df7\u5408\uff0c\u8a66\u5716\u88fd\u9020\u985e\u6fb1\u7c89\u6591\u3002\u7fa4\u96c6\u7d20\u9019\u7a2e\u7269\u8cea\u662f\u7531\u963f\u8332\u6d77\u9ed8\u75c7\u60a3\u8005\u7684\u8166\u4e2d\u9ad8\u7d1a\u4e2d\u6a1e\u6240\u7522\u751f\uff0c\u5b83\u4e26\u672a\u4fc3\u4f7f\u985e\u6fb1\u7c89\u86cb\u767d\u6591\u7684\u5f62\u6210\uff0c\u4f46\u524d\u8ff0\u7684\u6df7\u5408\u6eb6\u6db2\u537b\u56b4\u91cd\u5e72\u64fe\u4e86\u795e\u7d93\u5143\u50b3\u905e\u8a0a\u606f\u7684\u80fd\u529b\u3002<\/p>\n
\u82ac\u5947\u5c07\u9019\u9805\u767c\u73fe\u544a\u77e5\u4e86\u7f8e\u570b\u897f\u5317\u5927\u5b78\u7684\u5169\u4f4d\u540c\u884c\uff0c\u514b\u62c9\u592b\u7279\u53ca\u514b\u840a\u6069\uff0c\u65bc\u662f\u514b\u62c9\u592b\u7279\u548c\u514b\u840a\u6069\u4fbf\u8457\u624b\u5c0b\u627e\u6eb6\u6db2\u88e1\u5230\u5e95\u6709\u4ec0\u9ebc\u6771\u897f\u3002\u5728\u539f\u5b50\u529b\u986f\u5fae\u93e1\u7684\u5e6b\u5fd9\u4e0b\uff0c\u4ed6\u5011\u767c\u73fe\u4e86\u5f9e\u4f86\u6c92\u4eba\u770b\u904e\u7684\u7279\u6b8a\u7403\u72c0\u7269\u666f\u89c0\u3002\u514b\u62c9\u592b\u7279\u56de\u61b6\u9053\uff1a\u300c\u90a3\u770b\u8d77\u4f86\u50cf\u5c0f\u9846\u7684\u5f48\u73e0\u3002\u5f8c\u4f86\u767c\u73fe\u73e0\u5b50\u88e1\u53ea\u6709\u5c11\u8a31\u7684\u985e\u6fb1\u7c89\u80dc?\u7d44\u5408\u5143\u4ef6\uff0c\u7136\u800c\u9577\u7e96\u7dad\u4e2d\u5305\u542b\u7684\u9019\u7a2e\u7d44\u4ef6\u6578\u91cf\uff0c\u5373\u4f7f\u4e0d\u5230\u767e\u842c\uff0c\u4e5f\u6709\u6210\u5343\u4e0a\u842c\u3002\u300d\u9019\u4e09\u4f4d\u79d1\u5b78\u5bb6\u6c7a\u5b9a\u5c07\u9019\u7a2e\u7269\u8cea\u53d6\u540d\u70baADDL\uff0c\u5373\u64f4\u6563\u6027\u03b2\u985e\u6fb1\u7c89\u86cb\u767d\u914d\u4f4d\u5b50\u7684\u7e2e\u5beb\u3002\u8a72\u5206\u5b50\u662f\u7531\u985e\u6fb1\u7c89\u524d\u9a45\u86cb\u767d\u884d\u751f\u800c\u4f86\uff0c\u5b83\u4e26\u4e0d\u805a\u96c6\u6210\u56fa\u5b9a\u7684\u6591\u584a\uff0c\u53cd\u800c\u5728\u8166\u4e2d\u56db\u8655\u64f4\u6563\uff0c\u4e26\u50cf\u914d\u4f4d\u5b50\u4e00\u6a23\uff0c\u8207\u795e\u7d93\u5143\u4e0a\u7684\u53d7\u9ad4\u76f8\u63a5\u3002<\/p>\n
\u514b\u840a\u6069\u88fd\u4f5c\u51fa\u6297\u9ad4\uff0c\u53ef\u4ee5\u986f\u793aADDL\u5982\u4f55\u8207\u6d77\u99ac\u7684\u795e\u7d93\u6a39\u7a81\u76f8\u63a5\uff0c\u800c\u5e72\u64fe\u4e86\u5f62\u6210\u77ed\u671f\u8a18\u61b6\u6240\u5fc5\u9700\u7684\u8a0a\u606f\u3002\u53bb\u5e74\u590f\u5929\uff0c\u514b\u840a\u6069\u3001\u514b\u62c9\u592b\u7279\u3001\u82ac\u5947\u53ca\u5176\u540c\u4e8b\u5728\u6b7b\u53bb\u7684\u963f\u8332\u6d77\u9ed8\u75c7\u60a3\u8005\u8166\u4e2d\u767c\u73fe\u4e86\u5de8\u91cf\u7684ADDL\uff0c\u53cd\u4e4b\uff0c\u6b63\u5e38\u4eba\u8166\u4e2d\u5e7e\u4e4e\u627e\u4e0d\u5230ADDL\u3002\u5c24\u6709\u751a\u8005\uff0c\u4ed6\u5011\u767c\u73fe\u53ea\u8981\u53bb\u9664\u4e86ADDL\uff0c\u5c0f\u9f20\u7684\u795e\u7d93\u5143\u5c31\u80fd\u904b\u4f5c\u6b63\u5e38\u3002<\/p>\n
\u7167\u514b\u62c9\u592b\u7279\u7684\u770b\u6cd5\uff0c\u986f\u7136\u963f\u8332\u6d77\u9ed8\u75c7\u7684\u6cbb\u7642\u4e4b\u9053\u662f\u53bb\u9664ADDL\uff0c\u6216\u662f\u9632\u6b62\u5176\u751f\u6210\u3002\u4ed6\u8a8d\u70ba\u6d88\u9664\u985e\u6fb1\u7c89\u86cb\u767d\u6591\u7684\u5617\u8a66\u662f\u8aa4\u5165\u6b67\u9014\uff0c\u56e0\u70ba\u7576\u795e\u7d93\u5143\u5df2\u7d93\u958b\u59cb\u6b7b\u4ea1\uff0c\u518d\u63a1\u53d6\u4efb\u4f55\u4ecb\u5165\u5617\u8a66\uff0c\u90fd\u70ba\u6642\u5df2\u665a\u3002\u4ed6\u8aaa\uff1a\u300c\u5c0d\u6211\u4f86\u8aaa\u4e8b\u60c5\u76f8\u7576\u6e05\u695a\uff0c\u6211\u5011\u628a90%\u7684\u963f\u8332\u6d77\u9ed8\u75c7\u7814\u7a76\u7d93\u8cbb\uff0c\u90fd\u6d6a\u8cbb\u5728\u7121\u610f\u7fa9\u7684\u4e8b\u60c5\u4e0a\u3002\u300d<\/p>\n
\u514b\u62c9\u592b\u7279\u3001\u514b\u840a\u6069\u53ca\u82ac\u5947\u4e00\u9762\u5efa\u69cb\u7406\u8ad6\uff0c\u4e00\u9762\u53d6\u5f97\u4e86ADDL\u7684\u5c08\u5229\u6b0a\uff0c\u540c\u6642\u9084\u6210\u7acb\u4e86\u4ed6\u5011\u81ea\u5df1\u7684\u516c\u53f8\uff1a\u654f\u92b3\u88fd\u85e5\uff08Acumen Pharmaceuticals\uff09\u3002\u6700\u8fd1\u8a72\u516c\u53f8\u4e26\u8207\u9ed8\u6c99\u6771\u85e5\u5ee0\u5efa\u7acb\u5408\u4f5c\u95dc\u4fc2\uff0c\u514b\u62c9\u592b\u7279\u89e3\u91cb\u9053\uff1a\u300c\u6bd4\u8d77\u50c5\u9760\u6211\u5011\u81ea\u5df1\uff0c\u8207\u9ed8\u6c99\u6771\u5408\u4f5c\u53ef\u4ee5\u8b93\u6297\u9ad4\u53ca\u75ab\u82d7\u7522\u54c1\u66f4\u5feb\u4e0a\u5e02\u3002\u300d<\/p>\n
\u9ed8\u6c99\u6771\u85e5\u5ee0\u5df2\u627f\u8afe\u63d0\u4f9b\u654f\u92b3\u88fd\u85e54800\u842c\u7f8e\u5143\uff0c\u4ee5\u53d6\u5f97\u6388\u6b0a\u4f86\u767c\u5c55\u5c0d\u6297\u963f\u8332\u6d77\u9ed8\u75c7\u7684\u6297\u9ad4\uff1b\u5982\u679c\u6210\u529f\u7684\u8a71\uff0c\u5c07\u518d\u63d0\u4f9b4800\u842c\u7f8e\u5143\u4ee5\u767c\u5c55\u53ef\u4e0a\u5e02\u61c9\u7528\u7684\u75ab\u82d7\u3002\u9019\u7b46\u9322\u52a0\u4e0a\u5176\u4ed6\u4eba\u58eb\u7684\u6295\u8cc7\uff0c\u5c07\u4f7f\u654f\u92b3\u88fd\u85e5\u80fd\u6839\u64daADDL\u8a2d\u8a08\u51fa\u5176\u4ed6\u4e09\u7a2e\u9632\u6cbb\u963f\u8332\u6d77\u9ed8\u75c7\u7684\u7b56\u7565\uff0c\u4ee5\u53ca\u53ef\u6aa2\u6e2c\u51fa\u8a72\u75c5\u521d\u671f\u75c7\u72c0\u7684\u8a3a\u65b7\u65b9\u6cd5\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"
\u9577\u4e45\u4ee5\u4f86\u79d1\u5b78\u5bb6\u90fd\u61f7\u7591\uff0c1907\u5e74\u7531\u963f\u8332\u6d77\u9ed8\u91ab\u751f\u767c\u73fe\u7684\u86cb\u767d\u8cea\u5718\u584a\u53ca\u7cfe\u7d50\uff0c\u53ef\u80fd\u9020\u6210\u795e\u7d93\u5143\u6b7b\u4ea1\uff0c\u4e26\u9032\u800c\u5f15\u767c\u963f\u8332\u6d77\u9ed8\u75c7 […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-262","post","type-post","status-publish","format-standard","hentry","category-9-"],"aioseo_notices":[],"jetpack_featured_media_url":"","_links":{"self":[{"href":"http:\/\/www.bluegtv.com\/index.php?rest_route=\/wp\/v2\/posts\/262","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/www.bluegtv.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.bluegtv.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.bluegtv.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.bluegtv.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=262"}],"version-history":[{"count":0,"href":"http:\/\/www.bluegtv.com\/index.php?rest_route=\/wp\/v2\/posts\/262\/revisions"}],"wp:attachment":[{"href":"http:\/\/www.bluegtv.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=262"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.bluegtv.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=262"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.bluegtv.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=262"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}